Hair length H765

59,90 €

Background

During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.The Fibroblast Growth Factor 5 (FGF5) determines the hair length. The Hair Length test (H765) tests for the genetic status of the FGF5-gene and has two variants (alleles). The allele S is dominant and results in short hair. Only when the dog has two copies of the recessive allele L the dog has long hair. Some breeds, such as Labradors, are fixed for the dominant allele S. Other breeds, such as Poodles, are fixed for the recessive allele L and some breeds, such as Dachshund, can have either long or short hair. In some breeds another, yet unidentified, mutation is present that influences hair length. This unidentified mutation is known to occur in Afghan Hounds, Yorkshire Terriers, and Silky Terriers.

Test specific information

Since 2015, two brands have been developed. CombiGen? is mainly directed at veterinarian applications, whereas CombiBreed? is mainly directed at breeders and/or owners.Detailed information about Coat Colours and Coat Variation is presented at www.pharmaDNA.com.

Age

The genetic factor is continuously present, and will always be visible.

Throughput

Normally the result can be expected within 15 working days. This turn-around-time starts when both the sample and the fully filled-out and signed submission form have been received.

Location of disease or trait

The hairlength can be assessed on the outside of an individual.

Breed dependence

For this test samples from all breeds are accepted.

Sample type

For this DNA test we accept the following materials: Semen, Blood EDTA, Blood Heparin, Tissue, Swab. Please contact PharmaDNA if you wish to submit other material as listed.

Result

An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.

Inheritance

This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous). Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.

Severity of Disease

Genetic characteristics are not a disease.

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