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Dog DNA testing illustration

Progressive Retinal Atrophy (IFT122-PRA) – Lapponian Herder

Code: H962

74,72 €

Sample details

One test – one sample. Animal and owner details are optional.

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Short description

Progressive Retinal Atrophy (PRA) is a large group of genetic diseases in which the retina gradually degenerates over time, causing a progressive loss of vision.

General information

Progressive Retinal Atrophy (PRA) is a large group of genetic diseases in which the retina gradually degenerates over time, causing a progressive loss of vision. This particular variant of PRA, found in the Lapponian Herder, is caused by a recessive mutation to the gene IFT122.

Specifications

Breeds

Lapponian Herder
Gene

IFT122
Chromosome

20
Mutation

c.3176G>A
Organ

Sensory organs
Specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Autosomal Recessive
Also known as

PRA; IFT122-PRA

Clinical features

Affected dogs start gradually losing vision in adulthood, presenting with typical ophthalmological signs of PRA such as hyperreflectivity of the retina. Past 9 years of age, PRA becomes more apparent, and may result in total blindness.

References

Pubmed ID: 33606121

Year published: 2021

Omia ID: 2320

Omia variant ID:

Turnaround information

  • 15 working days