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Dog DNA testing illustration

Severe Combined Immunodeficiency (SCID, PRKDC-related) – Jack Russel Terrier

Code: H423

74,72 €

Sample details

One test – one sample. Animal and owner details are optional.

Search by our number or the laboratory number. An unmatched number is saved as a previous / external reference. No new physical sample is needed.
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Short description

Severe combined immunodeficiency (SCID) is a immuno deficiency disorder in dogs.

General information

Severe combined immunodeficiency (SCID) is a immuno deficiency disorder in dogs. This test is specific for a variant found in Jack Russel Terriers and is caused by an autosomal recessive mutation in the PRKDC gene. Dogs with SCID can not produce a protein important for proper immune function. Dogs without a proper immune function are vulnerable to severe recurrent or chronic bacterial, viral and fungal infections.

Specifications

Breeds

Jack Russell Terrier
Gene

PRKDC
Chromosome

29
Mutation

c.10879G>T
Organ

Respiratory System
Specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Autosomal Recessive

Clinical features

Symptoms are observed at around 12 to 14 weeks of age and include failure to thrive, poor growth, weight loss, lethargy, diarrhea, vomiting and lack of palpable lymph nodes.

References

Pubmed ID: 11867233

Year published: 2002

Omia ID: 220

Omia variant ID:

Turnaround information

  • 15 working days