CMR1 (Canine Multifocal Retinopathy)
Code: H871
Short description
Canine multifocal retinopathy (cmr) is an ocular disorder (autosomal recessive ) characterised by multiple areas of retinal degeneration in multiple dog breeds.
General information
Canine multifocal retinopathy (cmr) is an ocular disorder (autosomal recessive ) characterised by multiple areas of retinal degeneration in multiple dog breeds.
Specifications
| Breeds | Cane Corso, American Bulldog, American Bully, Australian Shepherd, Boerboel, Bullmastiff, Dogue de Bordeaux, English Mastiff, Great Pyrenees, Perro de Presa Canario |
|---|---|
| Gene | BEST1 |
| Chromosome | 18 |
| Mutation | c.73C>T |
| Organ | Sensory organs |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Recessive |
| Also known as | cmr1 |
Clinical features
Signs of cmr1 develop around 13 weeks of age, and include multiple tan-pink subretinal patches in both the tapetal and the non-tapetal fundus along with focal areas of tapetal hyper-reflectivity. The lesions elevate the retina. They progress as the animal ages to focal areas of retinal degeneration and retinal pigment epithelial hypertrophy and pigmentation.
References
Pubmed ID: 17460247
Year published: 2007
Omia ID: 1444
Omia variant ID:
Turnaround information
- 15 working days