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Horse DNA testing illustration

Hoof Wall Separation Disease – HWSD

Code: P899

74,72 €

Sample details

One test – one sample. Animal and owner details are optional.

Search by our number or the laboratory number. An unmatched number is saved as a previous / external reference. No new physical sample is needed.
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Short description

Hoof wall separation disease (HWSD) is a genetic defect in horses that causes the hoof wall to crack, chip, and break easily, while the coronary band appears normal.

General information

Hoof wall separation disease (HWSD) is a genetic defect in horses that causes the hoof wall to crack, chip, and break easily, while the coronary band appears normal. Symptoms typically begin in young horses, and in severe cases, the horse may bear weight entirely on the sole of the foot. This abnormal weight-bearing can result in severe pain and lameness. The defect is caused by an autosomal recessive mutation in the serpin peptidase inhibitor, clade B (ovalbumin), member 11 gene (SERPINB11).

HWSD appears to occur in the Connemara Pony, Gypsy Vanner, Tinker and Irish Cob.

Specifications

Breeds

Gypsy Vanner, Irish Cob, Connemara Pony, Tinker
Gene

SERPINB11
Chromosome

8
Mutation

c.504_505insC
Organ

Skeletal system
Specimen

Hair, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Autosomal Recessive
Also known as

HWSD

Clinical features

Hoof wall separation disease (HWSD) manifests clinically as separation of the dorsal hoof wall along the weight-bearing surface of the hoof during the first year of life.

References

Pubmed ID: 25875171

Year published: 2015

Omia ID: 1897

Omia variant ID:

Turnaround information

  • 15 working days