Coat Colour Snowdrop
Code: P384
Short description
The snowdrop dilution gene (SLC45A2) is characterized by the dilution of both red and black pigment.
General information
The snowdrop dilution gene (SLC45A2) is characterized by the dilution of both red and black pigment. This type of dilution has previously been identified in Gypsy and Tinker horse breeds. The cause of the snowdrop dilution is an autosomal recessive single-nucleotide change within the SLC45A2 gene. The same gene in which variants are responsible for other horse dilutions such as Cream, Pearl, and Sunshine.
The Snowdrop dilution has been identified in Gypsy Vanners, Irish Cobs, and Tinkers and can appear phenotypically similar to cremello.
Specifications
| Breeds | |
|---|---|
| Gene | SLC45A2 |
| Chromosome | 21 |
| Mutation | c.305G>A |
| Organ | Integumentary System |
| Specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Incomplete Dominant |
Clinical features
Phenotypically, the snowdrop dilution appears similar to cremello. A single dose (one copy of the snowdrop allele) does not affect the coat colour of black, bay, or chestnut horses. However, a double dose (two copies of the snowdrop allele) will result in the snowdrop coat colour.
Additional information
This test specifically detects one mutation in the SLC45A2 gene that is associated with the Snowdrop dilution. Mutations in other dilution genes may produce coat colours that resemble Snowdrop. Please note that this test is based on an association study.
References
Pubmed ID: 31961951
Year published: 2020
Omia ID: 1344
Omia variant ID:
Turnaround information
- 15 working days