Coat Colour Splashed White 2
Code: P513
Short description
The White Spotting coat colour pattern in horses can be caused by any in a wide array of related mutations.
General information
The White Spotting coat colour pattern in horses can be caused by any in a wide array of related mutations. The resulting pattern can vary anywhere between white markings on the face and legs, up to a completely white coat. Depending on both breed and pattern, variants of the White Spotting phenotype may be referred to as Splashed White, Dominant White, Tobiano or Sabino, among others.
The specific variant analysed in this test, known as Splashed White 2 (SW2), is caused by an incomplete dominant mutation to the paired box 3 (PAX3) gene. It is found in the Lipizzaner horse, Noriker and Quarter Horse breeds and is recently renamed into Auditory-pigmentary syndrome.
Specifications
| Breeds | |
|---|---|
| Gene | PAX3 |
| Chromosome | 6 |
| Mutation | c.209G>A |
| Organ | Integumentary System |
| Specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Incomplete Dominant |
| Also known as | SW |
Clinical features
SW2 horses are often characterised by a large broad blaze, white markings on the legs, variable white spotting on the belly and blue eyes.
Additional information
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a horse's coat colour genetics.
White Spotting can be caused by a wide range of mutations. A white-patterned horse that tests as unaffected for a particular mutation will almost certainly be affected by a different one.
References
Pubmed ID: 22511888
Year published: 2012
Omia ID: 1688
Omia variant ID:
Turnaround information
- 20 working days