Skip to main content

Address

Panerių g. 246
48454 Kaunas
Lithuania

Opening hours

  • Mon – Fri
    9 :00 – 17 00
  • Sat
    Closed    
  • Sun
    Closed   
Dog DNA testing illustration

Xanthinuria, type 2 – Manchester Terrier

Code: H789

74,72 €

Sample details

One test – one sample. Animal and owner details are optional.

Search by our number or the laboratory number. An unmatched number is saved as a previous / external reference. No new physical sample is needed.
The add to cart button will appear once you select the values above

Short description

Xanthinuria is a metabolic disorder that causes an excess of xanthine in the urine, which leads to the formation of urinary stones and related complications.

General information

Xanthinuria is a metabolic disorder that causes an excess of xanthine in the urine, which leads to the formation of urinary stones and related complications. Type II xanthinuria is caused by a recessive mutation to the gene MOCOS. The variant of the disorder analysed in this test is found in the Manchester Terrier. Related variants have also been observed in the Cavalier King Charles Spaniel and in the Dachshund.

Specifications

Breeds

Manchester Terrier (Standard), Manchester Terrier (Toy)
Gene

MOCOS
Chromosome

7
Mutation

c.232G>T
Organ

Urinary system
Specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Autosomal Recessive

Clinical features

Symptoms of xanthine urinary stones can include straining to urinate, frequent urination, bloody urine and in advanced cases life-threatening urinary tract obstruction. The disease can present anywhere between several months and several years of age.

References

Pubmed ID: 34584846

Year published: 2021

Omia ID: 1819

Omia variant ID:

Turnaround information

  • 15 working days