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Dog DNA testing illustration

Dilated Cardiomyopathy (DCM, PLN-related) – Welsh Springer Spaniel

Code: H865

74,72 €

Sample details

One test – one sample. Animal and owner details are optional.

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Short description

Dilated Cardiomyopathy (DCM) is a disorder of the heart, which grows too large and becomes unable to pump blood effectively.

General information

Dilated Cardiomyopathy (DCM) is a disorder of the heart, which grows too large and becomes unable to pump blood effectively. This can lead to irregular heartbeat and even sudden death. This variant of the disease, found in the Welsh Springer Spaniel, is caused by a dominant mutation to the gene PLN.

Specifications

Breeds

Welsh Springer Spaniel
Gene

PLN
Chromosome

1
Mutation

c.26G>A
Organ

Cardiovascular System
Specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Autosomal Dominant
Also known as

DCM

Clinical features

Affected dogs appear generally healthy, but are at risk of sudden death from heart failure, generally between two and three years of age. Veterinary examination of cardiac function will reveal ventricular dilation and arrhythmia. While DCM cannot be treated directly, proper medication can support heart function to improve the welfare of affected dogs as long as possible.

References

Pubmed ID: 30794913

Year published: 2019

Omia ID: 2195

Omia variant ID:

Turnaround information

  • 15 working days