Coat Colour K-Locus (Dominant Black)
Code: H819
Short description
Coat colour in dogs is controlled by a wide range of different genes working together.
General information
Coat colour in dogs is controlled by a wide range of different genes working together. These genes are often referred to as ‘loci’. The Dominant Black, or K-Locus, corresponds to the gene ‘beta-defensin 103’ (CBD103), which plays a significant role in pigmentation. A dominant mutation to CBD103, designated as K^B, results in an all-black coat colour. The recessive, unaffected allele of the K-Locus is designated as k^y, and results in lighter colours.
Specifications
| Breeds | All Breeds |
|---|---|
| Gene | CBD103 |
| Chromosome | 16 |
| Mutation | c.231_233del |
| Organ | Integumentary System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Dominant |
| Also known as | K-Locus |
Clinical features
Affected dogs (K^B/K^B or K^B/k^y) develop black coats, as long as they are not also affected by the recessive variant of the E-Locus (e/e). The black colour can be further modified by the effects of the B-Locus and D-Locus.
Additional information
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a dog's coat colour genetics.
References
Pubmed ID: 17947548
Year published: 2007
Omia ID: 1416
Omia variant ID:
Turnaround information
- 15 working days