Coat Colour Dun Dilution
Code: P660
Short description
The Coat Colour Dun dilution test tests for the genetic status of the TBX3 gene.
General information
The Coat Colour Dun dilution test tests for the genetic status of the TBX3 gene. This gene has three variants (alleles); allele D is dominant over the alleles nd1 and nd2; allele nd1 is dominant over nd2. The dominant allele D results in Dun dilution with primitive markings. Allele nd1 does not dilute the coat colour of the horse, primitive markings are present but the expression is variable. Allele nd2 does not have an effect on the basic colour.
Specifications
| Breeds | All Breeds |
|---|---|
| Gene | TBX3 |
| Chromosome | 8 |
| Organ | Integumentary System |
| Specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Dominant |
Clinical features
The Dun dilution gene lightens the coat colour of the horse by lightening the body colour, leaving the head, lower legs, mane and tail undiluted. Dun is also typically characterised by “primitive markings”, almost all dun horses possess at least the dorsal stripe, but the presence of the other primitive markings varies. Other common markings may include horizontal striping on the legs, transverse striping across the shoulders, and lighter guard hairs along the edges of a dark mane and tail.
Additional information
Horses can also carry mutations for other modifying genes which can further affect their coat colour.
Specific breeds are undefined.
References
Pubmed ID: 26691985
Year published: 2016
Omia ID: 1972
Omia variant ID:
Turnaround information
- 15 working days