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Dog DNA testing illustration

Mycobacterium Avium Complex (MAC) – Schnauzer

Code: H282

74,72 €

Sample details

One test – one sample. Animal and owner details are optional.

Search by our number or the laboratory number. An unmatched number is saved as a previous / external reference. No new physical sample is needed.
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Short description

Mycobacterium avium Complex (MAC) refers to a range of different mycobacteria species, which are capable of causing infection and diseases in a wide array of animals.

General information

Mycobacterium avium Complex (MAC) refers to a range of different mycobacteria species, which are capable of causing infection and diseases in a wide array of animals. Dogs are mostly resistant to MAC infection. However, certain lineages of (Miniature) Schauzers show increased vulnerability to developing these infections. Research has shown this susceptibility to be caused by a recessive mutation to the gene CARD9.

Specifications

Breeds

Schnauzer (Miniature)
Gene

CARD9
Chromosome

9
Mutation

c.493-495delAAG
Organ

Immune System
Specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Autosomal Recessive
Also known as

MAC

Clinical features

Dogs affected by the mutation analysed in this test may develop MAC infections.

Symptoms of MAC infection can include anorexia, lethargy, diarrhea, lameness, fever, and anemia. Precise symptoms are dependant on the location and severity of the infection. MAC infections can be severe and contagious, and are likely to lead to death or require euthanasia on humane and safety grounds.

References

Pubmed ID: 38710903

Year published: 2024

Omia ID: 2854

Omia variant ID:

Turnaround information

  • 15 working days