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Dog DNA testing illustration

Haemophilia A – Labrador Retriever

Code: H286

74,72 €

Sample details

One test – one sample. Animal and owner details are optional.

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Short description

Haemophilia A, also called Factor VIII Deficiency, is the most common bleeding disorder in dogs.

General information

Haemophilia A, also called Factor VIII Deficiency, is the most common bleeding disorder in dogs. Caused by an X-linked recessive mutation to the gene F8, the disease strongly impairs the blood’s ability to clot, which can lead to severe symptoms such as spontaneous internal bleeding, or uncontrolled bleeding after injury or surgery.

This specific variant of the disease is found in the Labrador Retriever. Other variants are found in multiple breeds, such as the German Shepherd, Rhodesian Ridgeback and Irish Setter.

Specifications

Breeds

Labrador Retriever
Gene

F8
Chromosome

X
Mutation

c.2923_2924delGA
Organ

Cardiovascular System
Specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

X-Linked Recessive
Also known as

FVIII

Clinical features

Common clinical signs in dogs include bleeding from the mouth, subcutaneous and intramuscular haematomas and lameness.

References

Pubmed ID: 37438956

Year published: 2023

Omia ID: 437

Omia variant ID:

Turnaround information

  • 15 working days