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Dog DNA testing illustration

Congenital Idiopathic Megaesophagus (CIM) – German Shepherd

Code: H271

74,72 €

Sample details

One test – one sample. Animal and owner details are optional.

Search by our number or the laboratory number. An unmatched number is saved as a previous / external reference. No new physical sample is needed.
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Short description

Congenital Idiopathic Megaesophagus (CIM) or Megaoesophagus is a disorder of the digestive tract in which the esophagus fails to properly function, resulting in difficulty swallowing and various complications.

General information

Congenital Idiopathic Megaesophagus (CIM) or Megaoesophagus is a disorder of the digestive tract in which the esophagus fails to properly function, resulting in difficulty swallowing and various complications. In the German Shepherd, CIM occurs twice as often in males as in females. Additionally, a mutation to the gene MCHR2 has been found to be linked with a greatly increased risk of developing CIM.

Specifications

Breeds

German Shepherd
Gene

MCHR2
Organ

Digestive System
Specimen

Copan eNAT swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Risk Factor
Chromosome

12
Also known as

CIM
Year Published

2022

Clinical features

Dogs suffering from CIM have an esophagus that cannot effectively perform peristalsis (the transport of swallowed food to the stomach), which results in a stretched esophagus and also causes coughing and regular vomiting. Affected puppies suffer reduced growth and fail to thrive, and are also vulnerable to complications such as aspiration pneumonia and bowel obstruction.

References

Pubmed ID: 35271580

Omia ID: 2716

Turnaround information

  • 15 working days